[Shanghai Science and Technology Commission: construction of Shanghai Biological big data platform] Shanghai Science and Technology Commission issued the Shanghai Computational Biology Innovation and Development Action Plan (2023-2025), which mentioned the construction of Shanghai Biological big data platform. Based on the existing data resources, we should further strengthen the guiding role of financial funds, build a "core + node" database system with unified standards and strengthened applications, and form China's independent and controllable data resources and core technology. strengthen the policy governance of data security and privacy protection, provide high-quality basic guarantee for the development of computational biology, and actively undertake the construction of the Yangtze River Delta node of the National Bioinformation Center.